Peyronie‘s disease is characterized by the formation of a rigid, fibrous plaque under the skin of the penis, potentially altering the shape and firmness of an erection. This condition can have physical and psychological effects and lead to complications including painful erections and impotency. Peyronie‘s disease may occur at any age, but most frequently in men over the age of 40. Although uncommon, it is possible for younger men to develop the disease.
Cause of Peyronie‘s Disease
The origin of Peyronie‘s disease is not fully understood, but it may be a result of:
- Traumatic injury to the penis
- Side effect of certain medications such as beta-blockers
- Family history
In some cases, Peyronie‘s disease may not be linked to an injury but may be inherited or related to an underlying condition.
Symptoms of Peyronie‘s Disease
The predominant symptom of Peyronie‘s disease is the hard scar tissue that forms on the penile shaft. This can sometimes cause the penis to curve while erect. It is also possible for the disease to display itself as divots or clefts in the skin of the penis. Other symptoms may include:
- Erectile dysfunction
- Painful erections
- Impotence
It is important to note that while these hardened lesions may be unsightly growths, they are not cancerous.
Diagnosis of Peyronie‘s Disease
Peyronie‘s disease is usually diagnosed during a physical examination by a doctor. The hard plaque can usually be felt with or without an erection. The following tests may also be used to properly diagnose the condition:
- Ultrasound
- X-ray
Diagnostic tests may be used to analyze the plaque, and check for the presence of calcification.
Treatment of Peyronie‘s Disease
Treatment for Peyronie‘s disease may vary. In some cases, doctors may have patient‘s monitor their condition before any treatment is recommended. Other types of treatment may include:
- Medications
- Radiation therapy to break up scar tissue
- Penile traction therapy
- Plague Removal Surgery
XIAFLEX is the only FDA approved non-surgical treatment option for Peyronie’s Disease. Xiaflex a prescription medicine used to treat adult men with Peyronie's disease who have a "plaque" that can be felt and a curve in their penis greater than 30 degrees when treatment is started.
XIAFLEX® injections work to help gradually break down your scar tissue (plaque) over 1 to 4 treatment cycles, with about 6 weeks in between. Your doctor will determine how many cycles you need.
How does XIAFLEX work?
When paired with daily penile exercises, there are enzymes in XIAFLEX that work together and are thought to gradually help break down the plaque that's causing a bend in your erection.
How long is XIAFLEX treatment?
A 24 week course of XIAFLEX includes 4 treatment cycles. You may need between 1 to 4 treatment cycles with about 6 weeks between each cycle. You and your doctor will discuss how many treatment cycles are right for you.
How may XIAFLEX help?
When paired with gentle stretching and straightening of the penis, XIAFLEX is proven to help gradually reduce erectile curvature. Individual results will vary.
How is XIAFLEX different from other options?
XIAFLEX is an FDA-approved injectable treatment for appropriate men with Peyronie's disease.
Can I get treatment from my regular urologist?
XIAFLEX should be injected into the plaque by a healthcare provider who is trained and experienced in treating adult men with Peyronie’s disease. Not all urologists have this training.
